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The actor’s death was attributed to the “acute effects of ketamine,” according to Matthew Perry‘s autopsy report, which raised doubts and concerns regarding the use of this drug. According to the report, Perry was receiving ketamine infusion therapy and had only had one infusion prior to his death.

Matthew Perry cause of death listed as effects of ketamine, autopsy says :  NPR

The study also identified the effects of buprenorphine, drowning, and coronary artery disease as contributing factors to his demise. What then is this “fatal” depression medication that turned out to be the cause of Perry’s demise?

“Ketamine therapy is used to treat depression, anxiety, PTSD, end-of-life distress, chronic pain, drug/alcohol problems, and more,” according to the Pacific Neuroscience Institute. On the other hand, buprenorphine, which was also discovered in Perry’s system, is typically used to treat opioid use disorder, according to the Substance Abuse and Mental Health Services Administration.

In reference to Matthew Perry’s passing, the Associated Press cited Dr. Andrew Stolbach as saying, “Using sedative drugs in a pool or hot tub, especially when you’re alone, is extremely risky and, sadly, here it’s fatal.”

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